Sunday, September 30, 2012

HIV 'made' new deadly Salmonella

An epidemic of a deadly strain of Salmonella has swept across the whole of Africa by "taking advantage" of the spread of HIV, according to an international team of researchers.

Their study, published in Nature Genetics, is the first to identify the separate cases as a single epidemic.

One in four people in Africa infected with the strain died.

It is thought to be the first time a single strain of an infection has spread so widely in the wake of HIV.

Cases of this form of invasive non-typhoidal Salmonella have been recognised in Africa for more than a decade. It causes fever, headaches, respiratory problems and sometimes death.

Continue reading the main story

?Start Quote

It quite clearly parallels the emergence of HIV in Africa?

End Quote Prof Gordon Dougan Sanger Institute

The research team analysed the genetic code of 179 batches of Salmonella from different parts of Africa and the rest of the globe. Using techniques similar to a large-scale DNA paternity test, they were able to construct the strain's "family tree" and then how it spread.

It happened in two waves. The first started in south-eastern Africa about 52 years ago and the second wave started 35 years ago from the Congo Basin.

Prof Gordon Dougan, from the Sanger Institute in Cambridge in the UK, told the BBC: "It quite clearly parallels the emergence of HIV in Africa."

HIV attacks the immune system and leaves people more vulnerable to other infections. It is thought the strain of Salmonella Typhimurium took advantage of this weakness and spread. The research team said the bacterium was given the chance to "enter, adapt, circulate and thrive".

There is poor monitoring data for the disease across the whole of the continent, but Prof Dougan said it was affecting "thousands and thousands" of people and that 98% of adult cases were in people with HIV.

Continue reading the main story

?Start Quote

It's actually quite a huge problem and it seems to be getting worse because there are many susceptible people, it's got a grip in Africa?

End Quote Prof Brendan Wren London School of Hygiene and Tropical Medicine

He said this spread of Salmonella Typhimurium had been different to that of other infections commonly associated with HIV, as it had been a single epidemic "people were completely unaware" of and there "were not really any other examples" of that happening.

Dr Melita Gordon, a gastro-enterologist at the University of Liverpool, said: "It's the first time this has been described right across a continent in such an obvious way."

She added: "The highest mortality associated with the disease is 80%. What's happened over the years is mortality has fallen down and down and down to between 20% and 25% as doctors inside Africa recognise it."

The genetic analysis also showed the strain was resistant to the first choice antibiotic, chloramphenicol, which means more expensive drugs would be needed to treat the infection.

It is thought that improving HIV treatment across Africa could reduce the prevalence of the Salmonella infection, as it would reduce the number of people with vulnerable immune systems. However, the researchers urged "vigilance" in case the Salmonella strain mutated again to become able to infect people with healthy immune systems.

Commenting on the study, Prof Brendan Wren, from the London School of Hygiene and Tropical Medicine, told the BBC: "It's actually quite a huge problem and it seems to be getting worse because there are many susceptible people, it's got a grip in Africa.

"HIV, I think it's fair to say, provided a springboard for it to take off."

However, he thought the disease was "near its peak" as HIV was more controlled in other continents giving it little room to spread.

Source: http://www.bbc.co.uk/news/health-19727630#sa-ns_mchannel=rss&ns_source=PublicRSS20-sa

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Get Some Idea On The Advantages Of Web Hosting reviews ...

With the advent of internet and technology since the last few years a number of people who are business oriented have started using the Internet to serve their business purposes. With the cyber or internet business is getting more and more profitable every day most of all people have turned towards online business to make money while investing almost nothing. Since the last 15 years a number of organizations who are in need of cost effective hosting are skyrocketing continuously. If we consider the amount of businesses that are needed to be hosted then we can also get to see that the number of the web hosting companies or the web hosting service providers has also increased a lot as more and more individuals are turning towards this business considering it to be a lucrative one. Most of all the young entrepreneurs who are seeking to get foothold in internet business are starting with hosting service providing business.

But all web hosting companies do not create the same impact and this type of business can leave some business owners, who are involved in businesses like real estate and other instead of information technology, leave confused. Most of the time these business men waste most of their precious times in search of a standard web hosting service provider who can offer them the best deal that will fit their budget and fulfill their needs and requirements. Most of the inexperienced and ordinary service providers find it difficult to purchase the exact amount of web space or the necessary bandwidth that saves lots of money. ?Selecting the exact location of the server and the operating system along with assuring the customers that the host they have selected are reliable and capable enough to offer effective business support with the help of their qualified professionals are extremely necessary. It is quite necessary because you may find a number of examples where you can see that instead of having a thorough planning and sufficient budget many companies and businesses faced doom only because of the incapability of their web hosting service providers.

A qualified and skilled entrepreneur will surely take the advantages of the upcoming flow of the web hosting companies to develop a tailor made package that will perfectly suit his purposes and budget. But this is not at all an easy task to find the perfect hosting company or an individual. It requires lots of time, effort and hard research works.

Web hosting reviews such as Kate?s Hosting Reviews are mostly enlisted by the customers who have used their services and therefore, are ready to share their feedbacks and suggestions related the companies. All these reviews and feedbacks which in many cases are also inserted in the sites of the webhosting companies or the individuals help them to get a place of their own in the mist of the customers and in the pages of the search engines like Google, Bing etc.

Genelia Lopez is an expert author who has profound knowledge on web hosting and has written many reviews including Kate?s hosting reviews online.

Source: http://www.moderndignity.com/get-some-idea-on-the-advantages-of-web-hosting-reviews/

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Reply - USVI Moving Center

hello,

Rental:
Does anyone have any 1bedroom rentals in St John. Looking for a safe clean unit can be condo,apt, loft doesnt really matter for a 6 month or 1 year lease. I am trying to move to the island in next 30 days before season starts. Giving up on the rat race here in the states and gonna come try island life. Can pay several months up front if necessary.

Jobs:
I am33 year old working currently in medical device sales here in the states and very excited about a possible move to the islands. I have experience in mortgages/real estate prior to getting into medical device sales and would be willing to even bartend or wait tables as i did that working through college. Dont get me wrong i like to have fun but i need to work to be able to stay on the island long term.

Thanks,
Adam Silber
adam.silber@acutemedco.com

Source: http://www.vimovingcenter.com/talk/read.php?4,188920,188920

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IRL: Dyson DC44, NUU ClickMate PowerPlus and the Galaxy S III

Welcome to IRL, an ongoing feature where we talk about the gadgets, apps and toys we're using in real life and take a second look at products that already got the formal review treatment.

Can't get more random than this, folks: in this week's edition of IRL, we have Darren recommending a vacuum cleaner, Dan Cooper continuing his search for a backup phone charger and Jon Fingas putting the Galaxy S III to the test against his beloved HTC One X.

Continue reading IRL: Dyson DC44, NUU ClickMate PowerPlus and the Galaxy S III

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IRL: Dyson DC44, NUU ClickMate PowerPlus and the Galaxy S III originally appeared on Engadget on Sun, 30 Sep 2012 15:15:00 EDT. Please see our terms for use of feeds.

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Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/-4WHMg8PYJ0/

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0 comments - Real Life Husband RockStar Dad Blog!

In these upside down days of pre-manufactured "stars and starlets", who inexplicably gain fame for bad behavior, it's difficult for a young person to find quality role models in today's entertainment world.

A quick internet scan of the daily news inevitably brings multiple stories of terrible behavior by reality stars and music personalities. ?A quick scan of the songs currently being marketed as popular music inevitably leaves the listener's ears filled with obscenities and tales of debauchery.

Cimorelli, the marvelous sextet?of singing sisters, is staking their claim to Pop Music Royalty by doing all the right things. ?Raised in a loving two-parent home, this family group solidly stands ready to conquer the world by using their natural God-given talents to achieve success. ?Their wholesome approach to entertaining an audience is a quality that has been sorely lacking in the music business.

There is nothing pre-manufactured here...they are really talented, they are really dedicated, they are really grounded, and they are really sisters.

Cimorelli will win over the world the old fashioned way...by being real.

On my final day of Cimorelli Week, I am thrilled to present:


Christina Cimorelli!

Christina, as you grow more popular by the minute, what's the hardest thing about being a "Cimorelli"?

? - For me, it's probably the lack of a normal routine and schedule in my life. ?I am a very organized person and I love to have a schedule days, weeks, months in advance. ?With our career, though, that's impossible. ?I don't know what I'm doing tomorrow. ?It could change this afternoon!

What's the most surprising thing to happen to you since the 'THE CIMFAM EP' was released?

? - Getting nominated for Teen Choice Award! ?That was so insane.

You all make it look so easy to perform in front of the camera. ?Is it as easy for you to perform in front of a live audience?

? - Live audience is very easy for us because we've done years of theatre!

Any advice to overcoming stage fright?

? - My advice to people with stage fright is to do lots of theatre and perform as much as you possibly can even if you're terrified because it gets SO much easier each time! ?I used to be so scared and nervous and shy onstage but through my experience, I've become very comfortable. ?Also, PRACTICE. ?Practice, practice, practice! ?The more you practice, the more comfortable you will feel when you perform. ?Prepared = Confident.

On your approach to songwriting, you've said to "trust your instincts." ?Who else do you look to for honest feedback and direction when crafting an original song?

? - Whenever I finish a song, I show as many friends as possible. ?I love to see how they react to it and what really touches them. ?However, I really try to write things I like. ?If I write for others, it never turns out as genuine as I want. ?My best songs are the ones I just write for fun!

Outside of your family, who would you love to collaborate with?

? - Two people I would love to write with are Dr. Luke and also Max Martin. ?I think a Cimorelli collaboration with Diggy would be cool! ?Also, one with someone like Drake!

What's the most fun you've ever had with Lauren?

? - Probably every year on our birthday! ?We share a birthday, and it's in August, so it's always super summery and fun, and we always have a BLAST!

THANKS Christina!
It's hard to believe that you were ever shy on a stage, so your advice is wonderful.

Well readers...that concludes Cimorelli Week here on RealLifeHusband.com and I want to thank everyone that has stopped by to show your love. ?It has been a blast!
Please follow Christina on Twitter @ChristinaCim

THANKS CIM FAM! ?Your dedication to this group is an absolute joy!

THANKS CIMORELLI! ?I wish you wild success and I hope you always enjoy the ride.
Keep going and keep smiling...

I leave you all with a cool video of a song written by Christina and Lauren featuring the entire family! ?From 2008, here's the ridiculously catchy 'Delaney'...

Source: http://www.reallifehusband.com/2012/09/cimorelli-week-christina-cimorelli.html

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A glimpse of dying from literary authors | #AsiaMed Healthcare ...

?Medical training rarely deals with helping the dying patient find peace and comfort. In fact, most physicians are uncomfortable with the entire subject. I believe it is one of the most neglected aspects of medical care. I have spent my career as a pulmonary and critical care physician, and I have cared for thousands of dying patients. In many cases, both the patients and I knew that they were dying. After I provided clinical and supportive care, I would walk away from their bedside and go on with my work and go home to my family. Now the world has turned around for me. I have widespread metastatic disease to my lungs and bones.?

This was written by the prominent physician educator Roger Bone as he was dying and exploring the classical literature about death and dying. In Bone?s extensive search of classical literature he found little to explain death itself.

?In summary, the great classics, the most significant works in literary history, have had a seminal effect on the behavior and attitudes of our world today, concerning themselves as they do with the issues of love, tragedy, seduction, pride, intrigue, suspense, murder, vanity, fantasy, evil, cruelty, greed, adultery, deceit, depression, fear, brutality, hypocrisy, pride, chivalry, heroism, romance, honor, loyalty, and friendship. But only rarely do they deal with an understanding of death. Notable exceptions include the passages visited above, most memorable in the scene of Beth?s death in Little Women, Emily?s death in Our Town, and Thoreau?s observations in Walden. I examined the classics closely for answers and was left with the conclusion that if you have limited time, read Thoreau, Alcott, and Wilder.?

Perhaps we can get a glimpse about the ?D? word from authors.

?Dying is a very dull, dreary affair. And my advice to you is to have nothing whatever to do with it.? (Somerset Maughan) Perhaps the denial that we all have is healthy to some degree, but ultimately harmful when we have to face and plan for the inevitable.

?It?s not that I?m afraid to die, I just don?t want to be there when it happens.? (Woody Allen) The point here is that we really do have some fear, and that denial can be humorous as long as we?re not facing a real crisis.

?Life is pleasant. Death is peaceful. It?s the transition that?s troublesome.? (Isaac Asimov) I often heard this from patients, ?It?s the dying I?m afraid of!?

Advance planning is something we, as a society, don?t do well. Most of us tend not to save adequately for retirement, don?t execute wills, and don?t complete advance directives. Appropriately we tend to live in the present, ?the now?. So how do we deal with educating ourselves, our leaders, and our governments to balance ?the now? with ?the future?. Ultimately the education about advance planning needs to come from the heath professions, medical societies, communities, states, and the federal government. Viewing this as a public health issue with the rapid aging of the population, the CDC has created a program to educate heath professionals.

None of this, of course, really addresses the mystery of what follows death. Roger Bone found his comfort in the Bible, Helen Keller in Swedenborg?s writings in Heaven and Hell, but the journey remains ours alone, hopefully with our creator gently carrying us.

-Jim deMaine is a pulmonary physician who blogs at End of Life ? thoughts from an MD.

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Source: http://myasiamed.wordpress.com/2012/09/30/a-glimpse-of-dying-from-literary-authors/

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Saturday, September 29, 2012

Builders offer?home buyers?credit rehab

Joe Raedle / Getty Images

Lennar Corp, whose sign is displayed in front of a home above, is among a number of homebuilders benefiting from putting buyers on fiscal rehab.

By Michelle Conlin, Reuters

In the post-housing crash world, Kelly and Jeff Clark are the kind of people who are not supposed to be able to buy a house.

For a down payment, they had exactly nothing. Their credit scores were sub-par. But this Christmas, the Clarks will move from their rundown rental into a brand new, four-bedroom home in an amenity-loaded development outside of Lakeland, Florida. All without paying a dime.

The Clarks were able to qualify for a mortgage because their builder, Southern Homes, spent the summer putting them through a financial boot camp. Bigger home builders such as D.R. Horton Inc, Lennar and PulteGroup Inc are also offering sophisticated financial advice to prospective home buyers who would not normally qualify for loans.

These fiscal rehabs are one reason many builders are boosting sales, even though mortgage lending is tight. Pulte said in July that its financial program could help its sales for some time. On Monday, Lennar Corp said revenue from home sales rose 33 percent last quarter from the same quarter a year earlier. Orders for homes rose 44 percent, helped by the 25 percent increase in membership in its Homebuyers Club since last year.

Providing financial therapy solves a huge problem for the builders: How to sell to first-time home buyers when s o many yo unger consumers a re s a ddled wi th student debt and ba d c redit.

The financial advisors go by names such as "mortgage advisors," "credit advocates" or "loan officers." They help prospective customers create budgets and slash spending. Both D.R. Horton and Lennar also help out with "credit repair," the practice of analyzing credit reports to determine the best stra t egies for raising scores as quickly as possible.

The buyers then get mortgages from the builders' own, in-house lending arms.

But consumer advocates say there is an obvious conflict when doling out financial advice. Instead of helping prospective customers maximize wealth, advocates say builders' advisors could be trying to suck as much money as possible out of buyers' pockets.

"What it does is create a captive consumer where the builder can charge a lot more," said Douglas Miller, executive director of Consumer Advocates in American Real Estate, a nonprofit.

?

Homebuilders are often helping buyers get government-backed loans that require no down payment, or a low down payment, so taxpayers could be on the hook if buyers can't repay their mortgages. Some consumer experts fear that, just five years after the biggest housing meltdown in generations, builders are up to their old tricks again.

"You have people applying for loans that there's no way they can pay, but it doesn't matter because the ability to repay isn't the basis of the loan. It's the ability to pass underwriting so the loan can be sold," says Washington, D.C.-based bankruptcy attorney, Brett Weiss.

Builders say they are putting people in homes they can afford and helping them achieve their dreams. Most loans that banks are underwriting now meet stringent government standards.

For buyers with enough cash and income, buying a home can lower monthly housing costs because mortgage rates are at r ecord lows an d rents are surging. Monthly mortgage costs are lower than rent in nearly every major U.S. metro area now, according to John Burns Real Estate Consulting.

Call whenever
Last year, executives at PulteGroup found that nearly 90 percent of younger buyers wanted to own a home. They loathed throwing away money on rent each month.

"The dream of American home ownership has not died at all," said Pulte Vice President of marketing Fred Ehle. "It was somewhat of a surprise to us."

But Gen X and Yers also had reservations about buying so soon after watching the housing market crash and burn. T hey also feared they would not qualify for a mortgage.

Just five years after the biggest housing meltdown in generations, that's led some consumer experts to fear that builders are up to their old tricks again.

The number of people aged 25-to-34 who bought homes in 2011 fell to 27 percent, the lowest share in the past decade, according to the National Association of Realtors. Rising student debt has played at least some role in that decline, analysts said. According to the U.S. Consumer Financial Protection Bureau, about 50 percent of young people that started college in 2003 were paying more than 10 percent of their income on student debt.

In response, Pulte launched a mortgage advisor program, whose members are buying houses at twice the rate of prospective purchasers who do not participate.

The advisors hand-hold customers through the entire home process, from picking the floor plan to arranging the mortgage to taking as many calls as necessary to assuage fears.

"I could call whenever I needed to with whatever I needed," says program member Erin Shafer, a 23-year-old school teacher who is buying a new home, along with her fianc?, in Woodstock, Illinois.

The couple have student debt, but they had enough for a down payment due to a relative's recent death. Pulte is giving them $5,000 for closing costs, $3,000 worth for free appliances and a mortgage.

The incubator
The Clarks thought they would remain renters forever. But early in the summer, a friend recommended that they meet with Janet Backman, a grandmotherly sales agent for Southern Homes.

During that first meeting, Backman pored over the Clarks' financials and decided to put them in what she calls her "Incubator."

That's the process Backman uses to convert the credit-challenged into home buyers within a matter of months. It drives her crazy that people in her area pay more to rent then to own.

The Clarks had no credit cards and paid for everything with cash. So as Backman talked with them that first day, she simultaneously signed them up for credit cards on the Capital One website.

Then she told the couple that, if they made $50 worth of purchases each month, but only paid the balance down to $25, their credit scores would likely rise immediately.

Within a month, Backman got the couple's scores up enough to qualify for the zero-down government-backed loan she secured for them through a partner lender.

Southern Home's sales agents have sold 162 homes so far this year, with nearly all getting similar advice and loan terms.

Says Backman: "Every time I hear about how hard it is to purchase a home, I'm thinking, what planet are they living on?"

More money and business news:

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Lennar, DR Horton and PulteGroup are all hitting multi-year highs. And Bill Mack, AREA Property, discusses opportunities in real estate.

Source: http://economywatch.nbcnews.com/_news/2012/09/28/14126352-homebuilders-put-buyers-into-credit-bootcamp?lite

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