headline news today: June 2013

Sunday, June 30, 2013

The Top 3 Places in Colorado Google Trekker Should Go

Do you get envious of people who tweet beautiful hiking pics while you?re stuck inside at work? You can have the last laugh with Google?s 15 lens camera.

You can now sign-up to borrow one of the company?s Trekkers, a soccer ball-shaped camera that captures a 360-degree panorama ? just like the Google Street View camera. As the Verge reports, Google previously only let select employees and a few third-party organizations take the Trekkers out to scenic places including the Grand Canyon and the Canadian Arctic, but now the company is giving any third-party organization the chance to apply online for loaner Trekker backpacks.

The footage that winning applicants capture could be added to Google's growing library of Street View scenes around the world, though its unclear for now just how much, if any, other monetary compensation Google will provide to volunteers.

Google has already mapped the wintertime slopes of Colorado. What about for summer scenes? With so many beautiful places in the state, where should Google Trekker go in Colorado?

Here are our top 3 picks.

Devil?s Head Trail

Although not as high profile as the other two on the list, Devil?s Head trail is 15 miles outside of Castle Rock and a great hike for kids. The 1.4 mile long trail is relatively easy, and takes approximately 45 to 90 minutes on a one way hike with an elevation gain of 940 feet. Once there, there are 143 steps to get to Devil?s Head Lookout, the last of the seven original Front Range Lookout towers still in service. Though over 20,000 people hike it every year, Devil?s Head Trail remains a Colorado secret.

West Maroon Trail

Though they feature prominently on King Soopers cards, the Maroon Bells are still one of the most stunning views in the state. The trail meanders through aspen and around Maroon Lake, all in the shadow of the Bells. This easy hike gives a sustained view rather than just at the end.

The Colorado Trail

Stretching almost 500 miles from Denver to Durango, the Colorado Trail is a great snapshot of the state. Trail users experience six wilderness areas and eight mountain ranges topping out at 13,271 feet, just below Coney Summit at 13,334 feet. The average elevation is over 10,000 feet and it rises and falls dramatically. Users traveling from Denver to Durango will climb 89,354 feet. Now who wants to carry Trekker the whole way?

Are you feeling inspired? You can apply here. Have a better suggestion? Let us know in the comments below.

Source: http://kunc.org/post/top-3-places-colorado-google-trekker-should-go

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China bank regulator says liquidity ample, debt risks manageable

By Gabriel Wildau and Samuel Shen

SHANGHAI | Fri Jun 28, 2013 11:16pm EDT

SHANGHAI (Reuters) - China's chief banking regulator said on Saturday that liquidity in China's banking system is sufficient and pledged to control risks from local government debt, real estate and shadow banking.

Despite a cash squeeze that sent money-market interest rates soaring over the last two weeks, banks have more than enough reserves to meet settlement needs, Shang Fulin, chairman of the Chinese Banking Regulatory Commission (CBRC), said at a financial forum on Saturday.

"Over the last few days, due to multiple factors, the problem of tight liquidity has appeared in the market. But overall, liquidity in our banking system really isn't scarce," Shang said at a speech to the Lujiazui Forum in Shanghai

Shang said total excess reserves in China's banking system totaled 1.5 trillion, which he said was more than double the amount necessary for normal payment and settlement needs.

On the issue of banks' asset quality and, in particular, banks' exposure to local government debt and the real estate market, Shang acknowledged risks but said they were manageable.

"Recently, some international organizations and industry insiders have expressed worry about a slowdown in China's economic growth, local government debt, the real estate market, and related areas," Shang said.

"Currently everyone is fully aware of the risks. As long as we take proper risk control measures, these risks are controllable," Shang said.

On local debt, Shang pledged to closely monitor and control the growth in local borrowing and "alleviate hidden risks".

Outstanding bank loans to local government financing vehicles totaled 9.59 trillion yuan at the end of the first quarter, Shang said.

Amid the cash squeeze earlier this month, CBRC repeated previous orders to banks to report all forms of local government debt exposure to regulators, including funds channeled through wealth management products (WMP).

The central bank, which had let short-term borrowing costs spike to record highs to drive home a message to banks that they could no longer count on cheap cash to fund riskier operations, said it would ensure policy supported a slowing economy. <CN/>

On the topic of WMPs, which have exploded in recent years as households and firms have searched for higher-yielding alternatives to traditional deposits, Shang said the development was positive but also highlighted risks.

"In reality, wealth management products are investment products. Wealth management products are not the same as savings. Investors have to bear investment risk. When banks do these products, are they clearly explaining the risks to investors?" Shang said.

Analysts have said that many WMP investors believe that many products carry an implicit guarantee from state-backed banks, even if no legal guarantee exists.

Bank-issued WMPs totaled 8.2 trillion yuan ($1.34 trillion) by the end of the first quarter, of which 70 percent were invested in the real economy.

Though Shang did not elaborate, the comments implied that the remaining 30 percent was invested in interbank assets, whose explosive growth was a key factor in the recent interbank liquidity squeeze.

On the real estate market, Shang downplayed the risk to the banking system, despite a three-year campaign by the central government to restrain housing prices.

Real estate loans totaled more than 13 trillion yuan by the end of April, of which mortgages comprised about 70 percent, Shang said.

"Chinese people are creditworthy. The non-performing loan ratio on mortgages is extremely low, far below 1 percent," Shang said.

(Editing by Michael Perry)

Source: http://feeds.reuters.com/~r/reuters/businessNews/~3/-7o8M5wCjYc/story01.htm

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Findings reported from Albert Einstein College of Medicine describe advances in diabetes

By a News Reporter-Staff News Editor at Clinical Trials Week -- Investigators publish new report on Diabetes. According to news reporting originating in Bronx, New York, by NewsRx journalists, research stated, "Obesity is important for the development of type-2 diabetes as a result of obesity-induced insulin resistance accompanied by impaired compensation of insulin secretion from pancreatic beta cells. Here, based on a randomized pilot clinical trial, we report that intranasal oxytocin administration over an 8-week period led to effective reduction of obesity and reversal of related prediabetic changes in patients."

The news reporters obtained a quote from the research from the Albert Einstein College of Medicine, "Using mouse models, we further systematically evaluated whether oxytocin and its analogs yield therapeutic effects against prediabetic or diabetic disorders regardless of obesity. Our results showed that oxytocin and two analogs including [Ser4, Ile8]-oxytocin or [Asu1,6]-oxytocin worked in mice to reverse insulin resistance and glucose intolerance prior to reduction of obesity. In parallel, using streptozotocin-induced diabetic mouse model, we found that treatment with oxytocin or its analogs reduced the magnitude of glucose intolerance through improving insulin secretion. The anti-diabetic effects of oxytocin and its analogs in these animal models can be produced similarly whether central or peripheral administration was used."

According to the news reporters, the research concluded: "Oxytocin and its analogs have multi-level effects in improving weight control, insulin sensitivity and insulin secretion, and bear potentials for being developed as therapeutic peptides for obesity and diabetes."

For more information on this research see: Treatment of obesity and diabetes using oxytocin or analogs in patients and mouse models. Plos One, 2013;8(5):e61477. (Public Library of Science - www.plos.org; Plos One - www.plosone.org)

Our news correspondents report that additional information may be obtained by contacting H. Zhang, Dept. of Molecular Pharmacology, Diabetes Research Center, Institute of Aging, Albert Einstein College of Medicine, Bronx, New York, United States (see also Diabetes).

Keywords for this news article include: Bronx, Obesity, New York, Diabetes, Treatment, Bariatrics, Proinsulin, United States, Overnutrition, Peptide Hormones, Diet and Nutrition, Nutrition Disorders, North and Central America, Clinical Trials and Studies.

To see more of the NewsRx.com, or to subscribe, go to http://www.newsrx.com .

Source: http://www.lef.org/news/LefDailyNews.htm?NewsID=19561&Section=Aging

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Saturday, June 29, 2013

How To Improve Your Credit Score For Better Financing Terms

How To Improve Your Credit Score For Better Financing Terms Imagine that you?ve found the perfect home and are ready to apply for financing. Your home loan approval amount comes back lower than you would have expected and at an interest rate significantly above what you have heard is available on the market.

This could be because you have an average to poor credit score.

Mortgage lenders base interest rates on many things, but your credit score plays a large part. Anything between 720 and 850 will typically qualify for better interest rates. A mediocre score is usually between 660 and 719, and a low score is 659 and under.

If you have a lower score than you?d like, below are a few traits for you to follow of people who possess higher credit scores and secure the best home financing.

They don?t max out their cards.

It?s better to keep a low revolving balance on a few cards than to spend every dime allotted on one. The ratio of credit card balance to your credit limit is called credit utilization. The higher your credit utilization, the larger affect it can have one your credit score.

They make payments on time.

This is very likely the most important tip for your credit health. If you miss a payment on a term loan, credit card account or monthly home bill, then you could be turned over to collections, which will affect your score negatively. ?You will almost surely be reported as late to the credit bureaus, which will in turn drop your credit score precipitously. Absolutely make all of your payments before their due date.

They stay with one card.

Don?t close and open credit card accounts frequently. Each time you make a change to your line of credit, it affects your score. Even if you don?t want to be tempted to use a credit card, keep the account open and leave the card at home. According to the Fair Isaac Corporation (FICO), high credit achievers have accounts that are usually at least 11 years old.

Excellent credit could qualify you for a better interest rate, which might save you thousands of dollars over the life of the loan. So stay on top of your monthly credit bills and keep a low balance on just a few cards to watch your score steadily increase.

If you?re ready to learn more about your ability to purchase a home, call your trusted home financing professional today.

Source: http://coolshax.mysmartblog.com/home-financing-tips/how-to-improve-your-credit-score-for-better-financing-terms/

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Young Imbeciles Destroy Largest Lego Helicopter Ever

Yesterday a group of idiots destroyed the largest Lego helicopter in the world, the 100,000-piece Erickson Air-Crane. Built by Ryan McNaught over the course of six weeks, the pieces alone are valued at $25,000.

The Gang of Eight?s Bill Will Never Become Law (Powerlineblog)

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Tiny nanocubes help scientists tell left from right

June 28, 2013 ? In chemical reactions, left and right can make a big difference. A "left-handed" molecule of a particular chemical composition could be an effective drug, while its mirror-image "right-handed" counterpart could be completely inactive. That's because, in biology, "left" and "right" molecular designs are crucial: Living organisms are made only from left-handed amino acids. So telling the two apart is important-but difficult.

Now, a team of scientists at the U.S. Department of Energy's Brookhaven National Laboratory and Ohio University has developed a new, simpler way to discern molecular handedness, known as chirality. They used gold-and-silver cubic nanoparticles to amplify the difference in left- and right-handed molecules' response to a particular kind of light. The study, described in the journal Nano Letters, provides the basis for a new way to probe the effects of handedness in molecular interactions with unprecedented sensitivity.

"Our discovery and methods based on this research could be extremely useful for the characterization of biomolecular interactions with drugs, probing protein folding, and in other applications where stereometric properties are important," said Oleg Gang, a researcher at Brookhaven's Center for Functional Nanomaterials and lead author on the paper. "We could use this same approach to monitor conformational changes in biomolecules under varying environmental conditions, such as temperature-and also to fabricate nano-objects that exhibit a chiral response to light, which could then be used as new kinds of nanoscale sensors."

The scientists knew that left- and right-handed chiral molecules would interact differently with "circularly polarized" light-where the direction of the electrical field rotates around the axis of the beam. This idea is similar to the way polarized sunglasses filter out reflected glare unlike ordinary lenses.

Other scientists have detected this difference, called "circular dichroism," in organic molecules' spectroscopic "fingerprints"-detailed maps of the wavelengths of light absorbed or reflected by the sample. But for most chiral biomolecules and many organic molecules, this "CD" signal is in the ultraviolet range of the electromagnetic spectrum, and the signal is often weak. The tests thus require significant amounts of material at impractically high concentrations.

The team was encouraged they might find a way to enhance the signal by recent experiments showing that coupling certain molecules with metallic nanoparticles could greatly increase their response to light (see: http://www.bnl.gov/newsroom/news.php?a=11157). Theoretical work even suggested that these so-called plasmonic particles-which induce a collective oscillation of the material's conductive electrons, leading to stronger absorption of a particular wavelength-could bump the signal into the visible light portion of the spectroscopic fingerprint, where it would be easier to measure.

The group experimented with different shapes and compositions of nanoparticles, and found that cubes with a gold center surrounded by a silver shell are not only able to show a chiral optical signal in the near-visible range, but even more striking, were effective signal amplifiers. For their test biomolecule, they used synthetic strands of DNA-a molecule they were familiar with using as "glue" for sticking nanoparticles together.

When DNA was attached to the silver-coated nanocubes, the signal was approximately 100 times stronger than it was for free DNA in the solution. That is, the cubic nanoparticles allowed the scientists to detect the optical signal from the chiral molecules (making them "visible") at 100 times lower concentrations.

"This is a very large optical amplification relative to what was previously observed," said Fang Lu, the first author on the paper.

The observed amplification of the circular dichroism signal is a consequence of the interaction between the plasmonic particles and the "exciton," or energy absorbing, electrons within the DNA-nanocube complex, the scientists explained.

"This research could serve as a promising platform for ultrasensitive sensing of chiral molecules and their transformations in synthetic, biomedical, and pharmaceutical applications," Lu said.

"In addition," said Gang, "our approach offers a way to fabricate, via self-assembly, discrete plasmonic nano-objects with a chiral optical response from structurally non-chiral nano-components. These chiral plasmonic objects could greatly enhance the design of metamaterials and nano-optics for applications in energy harvesting and optical telecommunications."

This research was conducted at the Center for Functional Nanomaterials and funded by the DOE Office of Science and by the National Science Foundation.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_technology/~3/hrpWn2kSSTU/130628102933.htm

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Molecule drives aggressive breast cancer

June 27, 2013 ? Recent studies by researchers at Thomas Jefferson University's Kimmel Cancer Center have shown a gene known to coordinate initial development of the eye (EYA1) is a powerful breast tumor promoter in mice. The gene EYA1 was also shown to be overexpressed in a genetic breast cancer subtype called luminal B.

The scientists found that excess activity of this gene -- EYA1 -- also enhances development of breast cancer stem cells that promote resistance to cancer therapy, recurrence, and poor survival.

Because EYA1 is an enzyme, the scientists are now working to identify a natural compound that could shut down EYA1 activity, says Richard Pestell, M.D., Ph.D., Director of Kimmel Cancer Center.

"It was known that EYA1 is over-expressed in some breast cancers, but no one knew what that meant," he says. "Our studies have shown the enzyme drives luminal B breast tumor growth in animals and the enzyme activity is required for tumor growth."

In a mouse model of aggressive breast cancer, the research team targeted a single amino acid on the EYA1 phosphatase activity. They found that inactivating the phosphatase activity of EYA1 stopped aggressive human tumors from growing.

"We are excited about the potential of drug treatment, because it is much easier to develop a drug that targets a phosphatase enzyme like EYA1, than it is to target a gene directly," he says.

Tracing how EYA1 leads to poor outcomes

The study, which was published in the May 1 issue of Cancer Research, examined 2,154 breast cancer samples for the presence of EYA1. The researchers then linked those findings to patient outcomes. They found a direct relationship between increased level of EYA1 and cyclin D1 to poor survival.

They then chose one form of breast cancer -- luminal B -- and traced the bimolecular pathway of how EYA1 with cyclin D1 increases cancer aggressiveness. Luminal B breast cancer, one of five different breast cancer subtypes, is a hormone receptor-positive form that accounts for about 20 percent of human breast cancer. It is more aggressive than luminal A tumors, a hormone receptor-positive cancer that is the most common form of breast cancer.

Their work delineated a string of genes and proteins that are affected by EYA1, and they also discovered that EYA1 pushes an increase in formation of mammospheres, which are a measure of breast cancer stem cells.

"Within every breast cancer are breast cancer stem cells, which give rise to anti-cancer therapy resistance, recurrence and metastases," Dr. Pestell says. "We demonstrated in laboratory experiments that EYA1 expression increase the number of mammospheres and other markers of breast cancer stem cells."

"As the EYA1 phosphatase activity drove breast cancer stem cell expansion, this activity may contribute to worse survival," he says.

This study was supported in part by the NIH grants RO1CA132115, R01CA70896, R01CA75503, R01CA86072 and P30CA56036 (RGP), a grant from the Breast Cancer Research Foundation (RGP), a grant for Dr. Ralph and Marian C. Falk Medical Research Trust (RGP), Margaret Q. Landenberger Research Foundation, the Department of Defense Concept Award W81XWH-11-1-0303.

Study co-authors are, from Kimmel Cancer Center: first author Kongming Wu, Zhaoming Li, Shaoxin Cai, Lifeng Tian, Ke Chen, Jing Wang and Adam Ertel; Junbo Hu, from Huazhong University of Science and Technology, China; and Ye Sun, and Xue Li from Boston Children's Hospital.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/jBYVoKY_n-o/130627190327.htm

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Friday, June 28, 2013

Weekend heat wave to bake western US

A construction worker is shown atop a roof at sunrise to beat daytime high temperatures, Thursday, June 27, 2013 in Queen Creek, Ariz. Excessive heat warnings will continue for much of the Desert Southwest as building high pressure triggers major warming in eastern California, Nevada, and Arizona. Dangerously hot temperatures are expected across the Arizona deserts throughout the week with a high of 118 by Friday. (AP Photo/Matt York)

Construction workers gather at a new home site at sunrise to beat daytime high temperatures, Thursday, June 27, 2013 in Queen Creek, Ariz. Excessive heat warnings will continue for much of the Desert Southwest as building high pressure triggers major warming in eastern California, Nevada, and Arizona. Dangerously hot temperatures are expected across the Arizona deserts throughout the week with a high of 118 by Friday. (AP Photo/Matt York)

Pre-dawn construction, to beat daytime high temperatures, continues on a new bridge, Thursday, June 27, 2013 in Mesa, Ariz. Excessive heat warnings will continue for much of the Desert Southwest as building high pressure triggers major warming in eastern California, Nevada, and Arizona. Dangerously hot temperatures are expected across the Arizona deserts throughout the week with a high of 118 by Friday. (AP Photo/Matt York)

Construction worker Joel Loza puts on his bandana after soaking it in water in an effort to keep cool Thursday, June 27, 2013 in Gibert, Ariz. Excessive heat warnings will continue for much of the Desert Southwest as building high pressure triggers major warming in eastern California, Nevada, and Arizona. Dangerously hot temperatures are expected across the Arizona deserts throughout the week with a high of 118 by Friday. (AP Photo/Matt York)

LAS VEGAS (AP) ? A high pressure system parking over the West is expected to bring temperatures this weekend and into next week that are extreme even for a region used to baking during the summer.

Notoriously hot Death Valley's forecast calls for 129 degrees, not far off the world record of 134 logged there July 10, 1913. The National Weather Service called for 118 in Phoenix, and at least 117 in Las Vegas on Sunday ? a mark reached only twice in Sin City.

"It's brutal out there," said Leslie Carmine, spokeswoman for Catholic Charities, which runs a daytime shelter in Las Vegas to draw homeless people out of the heat and set them up with sunscreen and bottled water.

Meteorologists are calling for highs at or above 112 through Wednesday in Las Vegas, and there isn't even relief when the sun goes down. Sunday night's low is forecast to be 92 degrees ? enough to make for a stuffy stroll down the Strip at whatever hour tourists leave the bar.

Two Elvis impersonators and a performer costumed as the iconic "Welcome to Fabulous Las Vegas" sign said they still planned to keep up their routine of working the tourist corridor in the broad daylight and turning in for the evenings, heat notwithstanding.

"We'd much rather fight with the sun than fight with the drunk people," Elvis impersonator Cristian Morales said Thursday.

While the Southwest boasts the most alarming temperatures, the heat wave is driving up the mercury all over the West. Western Washington ? better known for rainy coffee shop weather ? should break the 90s early next week, according to the weather service.

Dry southern Utah is forecast to reach higher than 110 degrees, and northern Utah ? which markets "the greatest snow on Earth" ? is also expected to hit the triple digits.

The heat wave is "a huge one," National Weather Service specialist Stuart Seto said. "We haven't seen one like this for several years, probably the mid- to late 2000s."

The system's high pressure causes air to sink and warm, drawing down humidity.

"As the air warms, it can hold more moisture, and so what that does is take out the clouds," Seto said.

While those in the West take to their swimming pools or hunker down indoors during the heat wave, the eastern half of the country is set for normal and below normal temperatures driven by lower pressure.

"There's a balancing act in the atmospheric pressure," said Chris Stachelski, a weather service meteorologist based in Las Vegas.

He noted that an unusual June heat wave that's had Alaskans shedding their polar fleece in favor of bathing suits is part of a separate high-pressure system centered in the Yukon.

The hottest cities in the West are taking precautions to protect vulnerable residents during the sizzle. Police are pleading with drivers not to leave babies or pets in vehicles, and temporary cooling stations are popping up to shelter homeless people and seniors on fixed incomes who hesitate to use the air conditioning.

Officials said extra personnel have been added to the U.S. Border Patrol's Search, Trauma, and Rescue unit as people illegally crossing the border from Mexico into Arizona could succumb to exhaustion and dehydration.

Several bodies of immigrants have been found in the last week in Arizona. Agents in the Tucson sector rescued more than 170 people from the desert during a 30-day stretch in May and June when temperatures were even lower than expected in the coming days.

At low-lying Lake Mead, which straddles the Arizona-Nevada border and is anticipating 120 degrees this weekend, rangers are positioned at trailheads to discourage hikers.

Earlier in June, a group of Boy Scouts hiking in the Colorado River canyon fell victim to soaring heat. Four teenagers and an adult had to be rescued, while a 69-year-old Scout leader died.

___

Associated Press writers Robert Jablon in Los Angeles, Julie Jacobson in Las Vegas, Michelle Price in Salt Lake City and Brian Skoloff in Phoenix contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-06-27-West%20Heat%20Wave/id-871968acd75749f49c622cdf668201ac

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Thursday, June 27, 2013

EU announces surprise deal on 7-year budget

BRUSSELS (AP) ? The European Union may soon have a new seven-year, 960-billion-euro ($1.27 trillion) budget after a surprise breakthrough deal on Thursday.

European Commission President Jose Manuel Barroso announced the agreement Thursday after early morning talks with the president of the European Parliament and other officials from EU member states. Barroso said the deal includes more flexibility than earlier versions.

It still needs final approval by the European Parliament, but that is looking more likely thanks to this agreement. European Parliament President Martin Schulz called the deal "acceptable" and said he's "optimistic" that he will have a majority of parliament members backing it at a vote next week.

It includes the first cut to spending in EU history at a time when many of the bloc's countries are in recession and struggling to reduce their own national debt. The budget sets what the EU can spend on everything from infrastructure and farming to development aid and employment measures.

The 27 EU countries have been trying since last fall to cobble together a budget for the years 2014-2020. The talks were tough because some countries wanted to increase or maintain spending levels while others insisted it made no sense to increase the EU's budget while individual governments were imposing tough austerity policies at home.

EU government leaders agreed to an overall package in February, but the European Parliament asked for more spending and more say in the way the budget will be handled.

Last week, leading parties in the European Parliament said they wouldn't back an earlier budget deal. Representatives of the Socialists said they backed the deal after winning some concessions.

Ireland's leader, Enda Kenny, championed the agreement. Ireland had been hoping to crown its six-month presidency of the EU that ends Sunday with a comprehensive budget agreement.

"We have concluded an agreement here today ... and I think it is very significant," he told reporters in Brussels alongside Barroso and Schulz. "At the beginning of this year there was a lot of doubt ... about whether compromise could be negotiated between member states and the parliament. We have now succeeded in doing that."

Countries such as Britain have argued that in a time of austerity the EU budget is a drag on national coffers, while others like France said the economic crisis highlighted the need for closer and deeper ties, which would compel the EU to do more ? and spend more ? than in the past.

Separate from national spending, the EU budget is designed in part to balance out the economic development of its members by injecting funding into poorer countries. The EU has funded thousands of infrastructure and capital projects over the years, from the installation of broadband networks to the upgrade of road networks.

The EU budget also includes items meant to generate economic growth, such as research and development, increasing digitalization and creating a new, more accurate satellite navigation system. It also funds regulation and administration in such areas as mergers and competition, the review of national budgets to ensure they do not include excessive deficits and banking supervision.

If the EU fails to get a seven-year deal passed by the EU Parliament before the end of the year, the EU would have to revert to annual budgets which would make long-term planning difficult.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-06-27-EU-Budget/id-be6c838dbe9345168b7a5d75b55cc3ca

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Marathon speech helps Democrats block Texas abortion bill (reuters)

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Senate immigration bill a ?pipe dream?

Illinois Republican Rep. Peter Roskam (Alex Wong/Getty Images)

The Senate is poised to pass a comprehensive immigration bill this week. Immigration reform proponents will cheer! Immigrant activists will cry tears of joy! DREAMers will dream bigger dreams!

Not to be a heartbreaker, but this party probably won't last long.

The Republican-controlled House of Representatives hasn't the slightest intention of passing the thing as a whole, says Illinois Republican Rep. Peter Roskam, a lawmaker responsible for counting Republican votes.

Roskam, who serves as the Republican chief deputy whip, made it clear on Thursday that House leaders do not plan to put the complete Senate bill to a vote on the floor of the lower chamber. Even if they did, it likely wouldn't pass.

?The House has no capacity to move that bill in its entirety. It just won?t happen," Roskam said during a meeting with reporters on Thursday morning. "It is a pipe dream to think that that bill is going to go to the floor and be voted on. The House is going to move through in a more deliberative process.?

While Senate members have agreed to take a comprehensive approach on the legislation?their bill would provide a pathway to legality for unauthorized immigrants and to spend billions on border security?House lawmakers intend to pass the bill in pieces, starting with a bill that shores up border security and then (maybe) another measure that deals with the 11 million people currently living in the United States illegally.

But that approach won't fly with Senate Democrats or President Barack Obama, who say they won't accept an immigration bill that doesn't have a pathway to legal status baked into the cake. Some might call it an impasse, a term more commonly referred to as just another day in Washington.

Unlike their counterparts in the Senate, who have taken steps to pass the bill quickly, the House is in no rush to act.

In one important way, the roles between the two chambers are reversed. There is a long-standing Washington tradition in which the House passes bills and the Senate ceremonially (and proudly) ignores them. This time, the House is the saucer that will cool the Senate's tea. Or, to put it another way, House Republicans want to slow-jam the immigration bill; Senate Democrats are thinking more Busta Rhymes.

For the moment, the House seems to be enjoying the role-reversal. Some aren't even reading the Senate version at all.

?I have not gone through chapter and verse on the Senate bill," Roskam said. "I don?t think I?m going to be voting on the Senate bill, so it?s not as if I?m marinating in study.?

Source: http://news.yahoo.com/blogs/news/senate-immigration-bill-pipe-dream-house-gop-lawmaker-155313110.html

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Wednesday, June 26, 2013

Koscielny 'addicted' to Premier League intensity | Arseblog News ...

Laurent Koscielny says he?s addicted to the intensity of the Premier League and joked that it?s his specialty to score important goals for Arsenal having netted on the final day of each of the last two seasons.

Speaking to regional press at the 50^th anniversary of local side FC Argentacois, the centre-back, who is finally on holiday having finished his international duties with France, reflected on a long season while answering the now customary questions about his future.

?I have a four-year contract and for now I?m at Arsenal,? the 27-year-old told lamontagne.fr when quizzed about the interest of Barcelona and Bayern Munich.

Stressing that he?s a self-confessed ?addict? of the Premier League, albeit one who is eager to ?keep working to improve?, the defender continued by expounding the qualities of English football.

?There is so much intensity, so much physical impact. The philosophy of the game is going from one goal to another. Every weekend the games are important when you?re selected.?

Asked about his winning goal against Newcastle United which secured Champions League football for Arsenal at the expense of Spurs, the Frenchman joked that it wasn?t the first time he?d come up trumps having done the same against West Bromwich Albion at the climax of the 2011/12 season.

?Last year, I also scored the goal that sent us in the Champions League. It has become my specialty!

Just kidding?the most important thing is that Arsenal is in the Champions League. It?s super exciting to play against the best teams in Europe.?

Looking ahead to pre-season with the Gunners, Kos also touched on the atmosphere in the camp and how he gets on with all his teammates.

?I feel good as part of the team. There are many different characters as in any professional environment. I am calm and I get along with everyone. There?s a good atmosphere amongst the group.?

There?s nothing particularly ground breaking in any of the above, but it?s good to hear Laurent is enjoying life in England.

____

Cheers to @SiuFay for the heads up.

8,961 views

Source: http://news.arseblog.com/2013/06/koscielny-addicted-to-premier-league-intensity/

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Gosselin: 'Slanted' eye photo a 'happy memory'

Celebs

Gael Fashingbauer Cooper and Randee Dawn TODAY

9 hours ago

Kate Gosselin has spoken out about the controversial photo in which she dons a plastic geisha-style wig and pulls her eyes up at the corners to imitate the look of an Asian person.

"This was a happy memory of mine," Gosselin wrote on her website. A fan had sent the plastic wig, Gosselin said, and she and husband Jon took turns wearing it and snapping photos. Gosselin added a photo of Jon in the wig to her site. "Naturally, I 'slanted' my eyes to show him my best Asian impression, which made him smile," she wrote.

Jon Gosselin was born in Wisconsin, and his parents are a mix of European and Korean descent.

"At that time, a common topic of our show was 'everybody?s Asian' ? except for mommy, so a thoughtful fan figured she?d help me look Asian too," Gosselin wrote.

"I married an Asian," she said in the post. "I have eight biracial children therefore I?m quite certain that I?m the last person that could be called a racist."

The photo of Gosselin making the gesture was distributed Sunday by someone calling him or herself "KatieDeen." That person created a fresh account on Twitter on Sunday evening, and posted just one item -- this picture, with the accompanying caption information suggesting that Gosselin "makes fun of Asians with 8 half Korean children."

Gosselin did not say if she knew who had published the photo, but did write that it "was taken and misused without my permission and opportunistically turned into something that it never was intended to be."

The gesture has caused controversy for others in the past, including in 2008 when the Spanish Olympic Team were photographed en masse for an advertisement making the gesture.

Source: http://www.today.com/entertainment/kate-gosselin-slanted-eye-photo-happy-memory-6C10435408

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'Independence Day' sequel: Would Will Smith return?

An 'Independence Day' sequel will reportedly take place 20 years after the first film. The film is scheduled to hit theaters in 2015.

By Sandy Schaefer,?Screen Rant / June 25, 2013

Would an 'Independence Day' sequel feature Will Smith?

Misha Japaridze/AP

Enlarge

It?s taken 17 years, but Fox has at last dated Independence Day 2 to hit theaters during (when else?) the Fourth of July holiday frame in 2015. The sequel will pick up in real-time, some twenty years after the first movie. However, co-writers Dean Devlin and Roland Emmerich (the latter is returning to direct) have revealed that ID4-2 takes place in an alternate present-day reality, where humanity has spent the last two decades harvesting the alien technology featured in the first movie.

Skip to next paragraph Screen Rant

Screen Rant had a humble start back in 2003 as a place to rant about some of the dumber stuff related to the movie industry. Since then, the site has grown to cover more and more TV and movie news (and not just the dumb stuff) along with sometimes controversial movie reviews. The goal at Screen Rant is to cover stories and review movies from a middle ground/average person perspective.

Tuesday, June 25, 2013

New screening approach identifies small proteins unique to melanoma cells, Moffitt researcher says

Public release date: 25-Jun-2013
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Contact: Kim Polacek
kim.polacek@moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute

Technique harnesses tumor-infiltrating lymphocytes to significantly improve outcomes

Jamie K. Teer, Ph.D., assistant member of the Cancer Biology and Evolution Program at Moffitt Cancer Center, and colleagues have developed a new streamlined method to rapidly identify the genetic changes in small protein fragments unique to melanoma cancer cells. These fragments can be used as targets for tumor-infiltrating lymphocytes that have been shown to reduce cancerous lesions.

The new approach is outlined in an article published online by Nature Medicine in May.

A previous phase 2 clinical trial showed substantial regression of metastatic lesions in up to 70 percent of melanoma patients who were treated with self-donated tumor-infiltrating lymphocytes.

"The trial, which involved the adaptive transfer of a patient's own immune cells, showed a complete tumor regression lasting at least five years in nearly 40 percent of the patients," Teer said. "To better understand how this works, researchers needed to identify tumor-infiltrating lymphocytes. We developed a new method to help do that more quickly."

Tumor-infiltrating lymphocytes are white blood cells that have left the bloodstream and migrated into a tumor. When numerous tumor-infiltrating lymphocytes are present, it suggests an immune response against the tumor. Research into quantifying the tumor-infiltrating lymphocytes and relating those numbers to tumor characteristics and outcomes has been carried out across many types of cancer.

According to Teer, a better understanding of how tumor-infiltrating lymphocytes induce cancer cell regression should increase the effectiveness of patient-donated cell therapy and also potentially reveal novel mechanisms of tumor growth. The technique uses next-generation DNA sequencing technologies to identify the changes that lead to the unique protein fragments.

"Our new technique allowed us to more quickly and easily identify mutated gene antigens recognized by T-cells in the immune system," explained Teer. "Work such as this was previously done by generating and laboriously screening DNA libraries from tumors. The same screening technique may be applicable for identifying mutated antigens in a variety of tumor types."

###

About Moffitt Cancer Center

Located in Tampa, Moffitt is one of only 41 National Cancer Institute-designated Comprehensive Cancer Centers, a distinction that recognizes Moffitt's excellence in research, its contributions to clinical trials, prevention and cancer control. Since 1999, Moffitt has been listed in U.S. News & World Report as one of "America's Best Hospitals" for cancer. With more than 4,200 employees, Moffitt has an economic impact on the state of nearly $2 billion. For more information, visit MOFFITT.org, and follow the Moffitt momentum on Facebook, twitter and YouTube.

Media release by Florida Science Communications

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

New screening approach identifies small proteins unique to melanoma cells, Moffitt researcher says

Public release date: 25-Jun-2013
[ | E-mail |

Share ]

Contact: Kim Polacek
kim.polacek@moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute

Technique harnesses tumor-infiltrating lymphocytes to significantly improve outcomes

The new approach is outlined in an article published online by Nature Medicine in May.

A previous phase 2 clinical trial showed substantial regression of metastatic lesions in up to 70 percent of melanoma patients who were treated with self-donated tumor-infiltrating lymphocytes.

###

About Moffitt Cancer Center

Media release by Florida Science Communications

[ | E-mail |

Share ]

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2013-06/hlmc-nsa062513.php

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Ailanthus tree's status as invasive species offers lesson in human interaction

June 24, 2013 ? An exotic tree species that changed from prized possession to forest management nightmare serves as a lesson in the unpredictability of non-native species mixing with human interactions, according to researchers.

"There are other invasive tree species in Pennsylvania, but the ailanthus, by far, has been here longer and does more damage than any other invasive tree," said Matthew Kasson, who received his doctorate in plant pathology and environmental microbiology from Penn State. "It's the number one cause of native regeneration failure in clearcuts in Pennsylvania."

Kasson, who is a post-doctoral researcher in plant pathology, physiology and weed science at Virginia Tech, said that William Hamilton, a pioneer botanist who corresponded with William Bartram and Thomas Jefferson, imported the first ailanthus altissima -- Tree-of-Heaven -- a tree native to China, from England sometime between 1784 and 1785 and cultivated the tree on his estate, the Woodlands, in Philadelphia. The deciduous tree, which grows rapidly, often to a height of 50 feet, has become one of the biggest forest management problems, especially since the 1980s, according to the researchers.

Kasson and colleagues report in a recent issue of the Northeastern Naturalist thatailanthus can invade quickly in areas where large, continuous stands of trees are cut down -- clearcuts -- and displace slower-growing native plants. The spread of ailanthus in Pennsylvania occurred in spurts that seem to be connected with stages of human development, particularly during cross-state transportation projects, Kasson said.

While the tree was initially isolated to the properties of a few botanists and wealthy plant collectors, commercialization of ailanthus after 1820 coupled with railroad construction projects that connected the eastern and western parts of the state in the mid-1800s intensified its spread, according to Kasson, who worked with Matthew Davis, lab assistant and Donald Davis, professor of plant pathology, both of Penn State.

In the 1980s, widespread gypsy moth infestation in Pennsylvania led to the death or near death of large stands of oak trees in the state forests, especially in south-central Pennsylvania. Crews that cut down the trees built roads to reach the sites, which became avenues for the spread of ailanthus. From 1989 to 2004 the number of Ailanthus trees on inventory plots increased from 76 million to 135 million.

In parts of the state forests there were no roads in areas associated with the gypsy moth devastation," said Kasson. "During these timber salvage operations, crews are building roads and moving a lot of soil and seed."

The researchers found one or two older female ailanthus trees near areas where foresters removed trees following the gypsy moth infestation, but also discovered that most of the ailanthus trees started to grow shortly after the clearing operation. The older seed-producing trees were often found upwind from the sites of the recent ailanthus growth. Kasson said this indicates that following the clearcut ailanthus grew faster than competing species and quickly dominated these forests.

Kasson said recent mining and drilling operations in Pennsylvania forests may also cause the species to expand.

"New roads are being constructed into these active drilling sites," said Kasson. "These drilling operations could lead to future spread."

Previous research may have also underestimated how long ailanthus can live, according to Kasson. While prior studies estimated that ailanthus's lifespan was between 50 to 75 years, the tree routinely lives longer than 100 years.

The researchers conducted tree-ring studies of ailanthus in all the counties where the tree grows in Pennsylvania, as well as several surrounding states. The researchers used these studies, along with historic surveys and reports on plant species in the state, to determine age and growth patterns.

Ailanthus, which is also calledChinese sumac or stinking sumac, grows in 60 of Pennsylvania's 67 counties, according to the researchers -- nine more counties than reported in previous studies. The research also suggests that the incidence of ailanthus in Pennsylvania's northern-tier counties, where the tree has been historically absent, will likely increase like previous ailanthus expansions in southern parts of the state.

The U.S. Department of Agriculture and Pennsylvania Department of Conservation and Natural Resources supported this work.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/8ry7-txpLx8/130624133134.htm

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Tool to detect hydrogen sulfide

June 24, 2013 ? University of Oregon chemists have developed a selective probe that detects hydrogen sulfide (H2S) levels as low as 190 nanomolar (10 parts per billion) in biological samples. They say the technique could serve as a new tool for basic biological research and as an enhanced detection system for H2S in suspected bacterially contaminated water sources.

Hydrogen sulfide, a colorless gas, has long been known for its dangerous toxicity -- and its telltale smell of rotten eggs -- in the environment, but in the last decade the gas has been found to be produced in mammals, including humans, with seemingly important roles in molecular signaling and cardiac health. Detection methods for biological systems are emerging from many laboratories as scientists seek to understand the roles of H2S in general health and different diseases.

Reporting in the Journal of Organic Chemistry -- online in advance of regular print publication -- researchers in the UO lab of Michael D. Pluth, professor of chemistry, describe the development of a colorimetric probe that relies on nucleophilic aromatic substitution to react selectively with H2S to produce a characteristic purple product, allowing for precise H2S measurement.

"This paper describes a new way to selectively detect H2S," said Pluth, who has been pursuing detection methods for the gas under a National Institutes of Health "Pathway to Independence" grant. That early career award began while he was a postdoctoral researcher at the Massachusetts Institute of Technology. "This technique allows you to use instruments to quantify how much H2S has been produced in a sample, and the distinctive color change allows for naked-eye detection."

In biological samples, he said, the approach allows for a precise measurement. In the environment, he added, the technique could be used to determine if potentially harmful H2S-producing bacteria are a contaminant in water sources through the creation of testing kits to detect the gas when levels are above a defined threshold.

The key to the technique, said the paper's lead author, doctoral student Leticia A. Montoya, is the reaction process in which the probe reacts with H2S to produce a distinctly identifiable purple compound. "This method allows you look selectively at hydrogen sulfide versus any other nucleophiles or biological thiols in a system," Montoya said. "It allows you to more easily visualize where H2S is present."

The chemical reaction produced in the experiments, Pluth said, also holds the potential to be applied in a variety of materials, on surfaces and films, with appropriate modifications. The UO has applied for a provisional patent to cover the technology.

The study is the second in which Pluth's lab has reported potential detection probes for H2S. Last year, in the journal Chemical Communications, Montoya and Pluth described their development of two bright fluorescent probes that sort out H2S from among cysteine, glutathione and other reactive sulfur, nitrogen and oxygen species in living cells.

"We're really interested in making sharper tools," Pluth said. "We have the basic science worked out, and now we want to move forward to fine-tune our tools so that we can better use them to answer important scientific questions."

"University of Oregon researchers are helping to foster a more sustainable future by developing powerful new tools and entrepreneurial technologies," said Kimberly Andrews Espy, vice president for research and innovation and dean of the UO graduate school. "This important research from Dr. Pluth's lab may someday alert us to environmental contaminants and could also impact basic science and human health."

Source: http://feeds.sciencedaily.com/~r/sciencedaily/matter_energy/biochemistry/~3/EospQ3KQMKU/130624133143.htm

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Monday, June 24, 2013

Apple allegedly looking into MacBook Air WiFi issue, replacing machines

Over the last few days we've been hearing from several of our readers about WiFi instability on new Haswell-equipped MacBook Airs, which also happens to be Apple's first computer with 802.11ac. Despite those rare reports, in our recent review it impressed us with solid performance and incredible battery life. Today 9to5Mac learned that Apple is supposedly aware of the issue and working on a fix, while some customers have also reported getting their systems replaced. In the meantime, the company has reportedly directed its Genius Bar employees to "capture" machines experiencing the problem -- i.e. return them to Cupertino for testing. We've contacted the company for comment and will keep you posted if there's any official response.

Filed under: Laptops, Apple

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Source: 9to5Mac

Source: http://www.engadget.com/2013/06/24/apple-allegedly-looking-into-macbook-air-wifi-issue-replacing-m/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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Funeral plans set for James Gandolfini

Concert goers display a photo of actor James Gandolfini during Day 2 of the Firefly Music Festival at The Woodlands on Saturday, June 22, 2013 in Dover, Del. (Photo by Owen Sweeney/Invision/AP)

NEW YORK (AP) ? Funeral services for actor James Gandolfini will be Thursday at the Cathedral Church of Saint John the Divine in New York City.

An HBO spokeswoman speaking on behalf of the family says the funeral is scheduled for 10 a.m.

The 51-year-old star of "The Sopranos" died Wednesday in Rome. Family spokesman Michael says Gandolfini died of a heart attack.

The Italian news agency ANSA reports Gandolfini's body departed Rome for the United States on Sunday. Kobold earlier told reporters the "provisional plan" was to repatriate Gandolfini's body Monday.

The actor had been headed to Sicily to appear at the Taormina Film Festival, which paid tribute to him Saturday.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-06-23-James%20Gandolfini/id-336433d33fc74ce790a84f59d9cdf016

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Arab Idol winner named UNRWA, goodwill ambassador

Palestinians watch the performance of Palestinian singer Mohammed Assaf, a contestant in a regional TV singing contest, on a large screen in the West Bank city of Nablus, Saturday, June 21, 2013. Palestinians relished a rare moment of pride and national unity Saturday after a 23-year-old wedding singer from a refugee camp in the Gaza Strip won ?Arab Idol,? a regional TV singing contest watched by millions of people. (AP Photo/Nasser Ishtayeh)

Palestinians celebrate after Palestinian singer Mohammed Assaf won a regional TV singing contest, in the West Bank city of Ramallah, Saturday, June 22, 2013. Palestinians relished a rare moment of pride and national unity Saturday after the 23-year-old wedding singer from a refugee camp in the Gaza Strip won ?Arab Idol,? a regional TV singing contest watched by millions of people. (AP Photo/Majdi Mohammed)

JERUSALEM (AP) ? The winner of the Arab Idol reality show can't stop adding titles.

After winning the popular contest, singer Mohammed Assaf was named a special ambassador Sunday by the U.N.'s Palestinian refugee agency and the Palestinian president.

On Saturday night, Assaf became the first Palestinian to win the Arab world's version of American Idol, setting off wild celebrations across the Palestinian territories.

After the victory, Palestinian President Mahmoud Abbas declared the singer an honorary ambassador. "I congratulate the talented singer Mohammed Assaf ... who conveyed the message of the Palestinian people to the Arab nation through his art," Abbas said in a statement distributed by the official Wafa news agency.

He was also named a named a youth ambassador by the U.N.'s Relief and Works Agency, which serves Palestinian refugees across the Middle East. The agency runs the Khan Younis refugee camp in Gaza, where Assaf has lived since the age of 4.

"All Palestinians share in his success," said the agency's commissioner, Filippo Grandi.

Assaf said he was "truly honored" by the appointment.

Assaf has emerged as a rare unifying force among Palestinians, who are divided between rival governments in the West Bank, where Abbas rules, and the Hamas-controlled Gaza Strip. The Palestinians hopes to establish an independent state in both territories, along with east Jerusalem.

Crowds gathered in the West Bank and Gaza late Saturday to watch the final episode of Arab Idol on big screens. After Assaf's victory was announced, fireworks lit up the sky over the West Bank and Gaza.

Many fans said the talented performer allowed Palestinians to forget about their political and geographic split. The Hamas militant group overran Gaza from Abbas' forces in 2007. Repeated attempts at reconciliation have failed.

Despite his popularity among Palestinians, Assaf's appearance on Arab Idol was criticized at first by Hamas. But with public opinion and Abbas' Fatah faction embracing Assaf, Hamas appeared to soften its stance on the competition.

Yehiyeh Moussa, a Hamas lawmaker in Gaza, this week praised Assaf as the "ambassador for Palestinian art."

Some hardline religious leaders have continued to criticize Arab Idol, calling the show blasphemous and immoral.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-06-23-Palestinians-Arab%20Idol/id-5152854b1c024347bec3f57ee103745d

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Tuesday, June 25, 2013

Technique harnesses tumor-infiltrating lymphocytes to significantly improve outcomes

Technique harnesses tumor-infiltrating lymphocytes to significantly improve outcomes

Monday, June 24, 2013